发明名称 METHOD FOR THE PREPARATION OF OXAZOLIDINES
摘要 <p>The novel oxazolidines of the formula <IMAGE> in which m is an integer from 1 to 4, X is hydrogen or alkoxycarbonyl, Y<1> and Y<2> are hydrogen or methyl, Z<1> is phenyl, phenoxy or phenoxymethyl, which is optionally ring-substituted by up to 3 substituents from the group consisting of halogen, hydroxyl, phenoxy, hydroxymethyl, nitro, amino, carbamoyl, trifluoromethyl, alkyl, alkoxy, alkanoylamino, alkoxybenzylamino and alkylsulphonylmethyl, Z<2> is a group of the formula <IMAGE> in which R<1>, R<2> and R have the meanings indicated in Claim 1, and the physiologically tolerable salts thereof have catabolic action and can be used for the treatment of obesity and diabetes or for the treatment of conditions which are associated with increased protein degradation, or as a food additive. They are prepared starting from corresponding 2-hydroxyethylamines.</p>
申请公布号 GR80889(B) 申请公布日期 1985.03.11
申请号 GR19898401808 申请日期 1984.11.08
申请人 F. HOFFMANN - LA ROCHE AND CO. 发明人 ALIG LEO;MULLER MARCEL
分类号 A61K31/42;A61K31/421;A61P3/06;A61P3/08;A61P3/10;C07D263/04;C07D263/06;C07D333/00;C07D333/38;C07D409/06;C07D413/06 主分类号 A61K31/42
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