摘要 |
A process for damage-free encapsulation of a variety of core materials including viable cells involves suspending the core material in an aqueous solution of a polysaccharide containing cationic groups, such as an aminated glucopolysaccharide. A temporary matrix is formed by gelling droplets of the suspension using a solution containing a divalent or multivalent anion. The temporary matrix is permanently cross-linked with a polymeric material containing plural anionic groups, e.g., polyaspartic or polyglutamic acid, to form a semipermeable membrane. The interior of the microcapsule may be resolubilized by subjecting it to a solution of low molecular weight cations. <IMAGE> |