发明名称 3-Imino-3H-dibenzo-[c,f]-imidazo-[1,5-a]azepine pharmaceuticals
摘要 Compounds of the formula <IMAGE> wherein R1, R2, R3 and R4 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy of 1 to 6 carbon atoms; R5 is hydrogen, alkyl of 1 to 6 carbon atoms or alkenyl of 3 to 6 carbon atoms; R6 is alkyl of 1 to 6 carbon atoms, alkenyl of 3 to 6 carbon atoms, phenyl, halo-phenyl, lower alkyl-phenyl, or lower alkoxy-phenyl or <IMAGE> R7 and R8 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy or 1 to 6 carbon atoms; n is an integer from 0 to 4, inclusive; x is -O-, -S-, or -CH2-; and the broken line between the 10 and 13b-positions indicates a single or double bond; and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as antiallergics and antithrombotics.
申请公布号 US4503060(A) 申请公布日期 1985.03.05
申请号 US19820410006 申请日期 1982.08.20
申请人 BOEHRINGER INGELHEIM KG 发明人 WALTHER, GERHARD;SCHNEIDER, CLAUS;WEBER, KARL-HEINZ;FUEGNER, ARMIN
分类号 C07D491/04;A61K31/55;A61K31/553;A61K31/554;A61P37/08;A61P43/00;C07D487/04;C07D495/04;C07D498/04;C07D513/04;(IPC1-7):A61K31/55 主分类号 C07D491/04
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