| 摘要 |
NEW MATERIAL:The primary alcohol derivative of phospholipid of formula I {A is group of formula II or formula III [R1 and R2 are -O-COR11 or -O-R12, or R1 and R2 in the group of formula II together form the group of formula IV (n is 11-19); R11 and R12 are 7-21C (un)saturated aliphatic hydrocarbon group]; R is 6-26C (except hexanol) (un)saturated aliphatic or aromatic hydrocarbon residue, etc., pregnan steroid compound residue, or heterocyclic compound residue such as pyridoxin, adenosin, etc.}. USE:Base for forming liposome, emulsifier for fat-based drug, or emulsifier for agricultural chemicals such as insecticide, herbicide, etc. PREPARATION:The phopsholipid of formula V [B is -(CH2)2N<+>(CH3)3, -(CH2)2NH2, -(CH2)mH (m is 1-5), etc.] is made to react with the primary alcohol of formula ROH in the presence of a phospholipase DM. |
