摘要 |
New azulene derivatives of the general formula …<CHEM>… where: R<1> is a lower alkyl group, a group of the general formula …<CHEM>… or a benzyl group, R<5>, R<6> and R<7> each representing H or a lower alkyl group and n being 1 or 2;… R<2> and R<3> each represents H or a lower alkyl group;… R<4> is H or an alkoxy group;… and X is Na or Al(OH)2 are stable to light and heat and are useful as anti-ulcerative and anti-inflammatory agents. …<??>The azulene derivatives may be prepared by reacting a compound of the formula …<CHEM>… wherein R<1>, R<2>, R<3> and R<4> are as defined above with a sulfonating agent and converting the resulting sulfonic acid to its sodium or aluminium salt. |