Substituted-aza-cytosine compounds and anti-viral uses thereof

摘要

Nucleoside analogues having a ring-open structure, of general formula: <IMAGE> where R and R' may be hydrogen, silyl groups, substituted alkyl groups, benzyl groups and the like, and X is an optionally substituted pyrimidine or triazine base, exhibit anti-viral activities e.g. against herpes simplex virus and cytomegalo-virus at non-toxic levels.