发明名称 Process for reducing blood sugar concentration in a mammal
摘要 A new class of arylsulfonylcarbamoyl-1,3-cyclohexanediones and arylsulfonylcarbamoyl-1,3-dicarbonylacyclic compounds are disclosed. These substances have hypoglycemic or hyperglycemic properties and are of value in controlling abnormal blood sugar levels. The arylsulfonylcarbamoyl derivatives of 1,3-dicarbonylalicyclic and acyclic compounds are prepared by reacting an arylsulfonylisocyanate with a 1,3-dicarbonylalicyclic or acyclic reactant. Typical embodiments are 2-(N-p-chlorobenzenesulfonylcarbamoyl)-5,5-dimethylcyclohexane-1,3-dione and 5-(1-ethylpropyl)-2-(N-p-chlorobenzenesulfonylcarbamoyl)-1,3-cyclohexa nedione.
申请公布号 US4093741(A) 申请公布日期 1978.06.06
申请号 US19760734154 申请日期 1976.10.20
申请人 MEAD JOHNSON & COMPANY 发明人 GRUNWALD, FREDERICK A.
分类号 A61K31/18;(IPC1-7):A61K31/18 主分类号 A61K31/18
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