发明名称 Derivatives of 4-phenyl-4-oxobuten-2-oic acid, pharmaceutical compositions containing them, and therapeutic uses for them
摘要 A compound of the formula I: <IMAGE> (I) in which R1 and R2 in any position on the benzene ring are different from each other, and independently represent a hydroxy group or an alkoxy group containing from 1 to 8 carbon atoms, or else R1 and R2 together form an -OCH2CH2O-radical, and R represents a hydrogen atom or an alkyl group containing from 1 to 8 carbon atoms, as well as the alkali metal, alkaline earth metal, ammonium or amine salts of the said products of formula I in which R represents a hydrogen atom. These compounds have been found useful in the treatment of hyperchlorhydria, gastric and gastro-duodenal ulcers, gastritis, hiatal hernias, and gastric and gastro-duodenal ailments accompanied by gastric hyperacidity. Pharmaceutical compositions including these compounds are disclosed along with methods for their production.
申请公布号 US4500731(A) 申请公布日期 1985.02.19
申请号 US19820435464 申请日期 1982.10.20
申请人 ROUSSEL UCLAF 发明人 BIANCHI, MARIO;BARZAGHI, FERNANDO
分类号 C07C69/738;A61K31/335;A61K31/357;A61P1/04;C07C51/00;C07C59/90;C07C67/00;C07D319/08;C07D319/18;(IPC1-7):C07C59/90 主分类号 C07C69/738
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