| 发明名称 |
ENZYME DERIVATIVES |
| 摘要 |
An enzyme derivative comprising Protein Ca in which the active site essential for anti-coagulant activity is blocked by an acyl group which is removable in vivo by enzymatic hydrolysis to provide a sustained and controlled release of Protein Ca. Preferred acyl groups are optionally substituted benzoyl or acryloyl groups. |
| 申请公布号 |
WO8500521(A1) |
申请公布日期 |
1985.02.14 |
| 申请号 |
WO1984GB00239 |
申请日期 |
1984.07.04 |
| 申请人 |
BEECHAM GROUP P.L.C. |
发明人 |
SMITH, RICHARD, ANTHONY, GODWIN;CASSELS, ROBERT |
| 分类号 |
A61K35/16;A61K38/00;A61K38/43;A61P7/02;C12N9/64;(IPC1-7):A61K35/16;A61K37/48 |
主分类号 |
A61K35/16 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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