| 摘要 |
<p>Novel peptides represented by the following formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="8" wi="81" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein; R<Sub>1</Sub> denotes pGlu, X-R<Sub>2</Sub>-CO-, X being carboxyl or amino and R<Sub>2</Sub> being lower alkylene of 1 - 6 carbon atoms, or
<Chemistry id="chema02" num="0002"><Image id="ia02" he="11" wi="41" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>A denotes Asp, Ala, or merely a chemical bond; B denotes Tyr(SO<Sub>3</Sub>H) or Phe(NHSO<Sub>3</Sub>H); C denotes Met or merely a chemical bond; D denotes Gly, D-Ala, or D-Trp; and Y denotes NH<Sub>2</Sub>, Asp-NH<Sub>2</Sub>, or Asp-Phe-NH<Sub>2</Sub>; with the proviso that Y is NH<Sub>2</Sub> or Asp-NH<Sub>2</Sub> when R<Sub>1</Sub> is pGlu, HOOC-R<Sub>2</Sub>-CO-, or
<Chemistry id="chema03" num="0003"><Image id="ia03" he="12" wi="39" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>B is Tyr(SO<Sub>3</Sub>H), C is Met, and D is Gly, and pharmacologically acceptable salts thereof.</p> |
