| 发明名称 |
Trans-3-carboxymethylene-4-carboxy-5-methyl-delta2-isoxazoline as intermediate |
| 摘要 |
Disclosed is a process for the stereocontrolled total synthesis of thienamycin, which synthesis proceeds via intermediate II: <IMAGE> II wherein R5 and R6 are removable protecting groups.
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| 申请公布号 |
US4499278(A) |
申请公布日期 |
1985.02.12 |
| 申请号 |
US19820443701 |
申请日期 |
1982.11.22 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
MELILLO, DAVID G.;RYAN, KENNETH M. |
| 分类号 |
C07D205/08;C07D261/04;C07D309/30;C07D477/04;C07F7/10;C07F7/18;(IPC1-7):C07D487/04;A61K31/40 |
主分类号 |
C07D205/08 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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