发明名称 Vesicles from dimeric acid derivatives, process for their preparation, and their use
摘要 Vesicles are described, composed of layers, which are probably monomolecular, of amphiphilic molecules and spacers defining the curvature, comprising: A I) alpha , omega -dicarboxylic acids and/or their derivatives having at least 14 C atoms as amphiphilic molecules and II) carbocyclic or heterocyclic amines having at least 5 ring atoms as spacers, the amines being present as ammonium groups and bound salt-like to a carboxylate function of the alpha , omega -dicarboxylic acid, or B I) alpha , omega -difunctional compounds having at least 14 C atoms as amphiphilic molecules and II) compounds having at least two polar functional groups and one carbocyclic or heterocyclic ring consisting of at least 5 atoms as spacers, one polar functional group of the spacer being covalently linked to a functional group of the amphiphilic molecule, a process is described for producing these vesicles, in which either an alpha , omega -dicarboxylic acid is suspended in water, an amine serving as a spacer having a carbocyclic or heterocyclic, at least 5-membered, ring is added in excess to the aqueous suspension, and the suspension is vigorously stirred or insonified with ultrasound, or an alpha , omega -difunctional compound having at least 14 C atoms is ... in a manner known per se with 1 to 2 mol of a compound having at least 2 polar functional groups and a carbocyclic or heterocyclic, at least 5-membered, ring, ... Original abstract incomplete.
申请公布号 DE3327645(A1) 申请公布日期 1985.02.07
申请号 DE19833327645 申请日期 1983.07.30
申请人 HENKEL KGAA 发明人 FUHRHOP,JUERGEN-HINRICH,PROF.DR.;KAUFMANN,WINFRIED;SCHAMBIL,FRED,DR.
分类号 A61K9/127;(IPC1-7):B01J13/02 主分类号 A61K9/127
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