发明名称 |
XENOGENEIC EXPRESSION CONTROL SYSTEM |
摘要 |
<p>A portable supplementary control system comprising a promoter/operator operably linked to a gene encoding the desired heterologous protein plus a gene encoding a compatible supplementary repressor protein operably linked to an inducible promotor, thus remedying any deficiency of repressor provided by the host's own genome, so that expression of a gene encoding a heterologous protein is repressed until a favourable point in the growth cycle of the host. The control system offers a method whereby heterologous protein production can be regulated by manipulation of the environment or of the medium.</p> |
申请公布号 |
GR80521(B) |
申请公布日期 |
1985.02.04 |
申请号 |
GR19218401805 |
申请日期 |
1984.10.02 |
申请人 |
GENENTECH INC. |
发明人 |
HEYNEKER LOUIS HERBERT;LIN CHSIANG SHIN NORM;PALMER THOURSON DONNA |
分类号 |
C12N15/09;C12N1/20;C12N15/63;C12N15/72;C12P21/00;C12R1/19 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|