发明名称 |
HYPOTRIGLYCERIDEMICALLY ACTIVE POLYSACCHARIDES |
摘要 |
A hypotriglyceridemically active polysaccharide having the following characteristics: (a) Specific rotatory power: [ alpha ]D29=+190.1 (1.8 w/v % solution) (b) Molecular weight by gel filtration: 14,000+/-3,000 (c) Sugar composition (weight percent by gas chromatography) glucose: 70.3 rhamnose: 13.7 uronic acid: 16.0 (d) Acid-base characteristic: neutral polysaccharides (e) Physiological characteristics: capable of reducing the blood triglyceride in mammals. This hypotriglyceridemically active polysaccharide can be prepared by cultivating a microorganism belonging to the genus Streptococcus in an adequate culture medium therefor; and collecting the hypotriglyceridemically active polysaccharide from the cultured cells of the microorganism and/or the supernatant of the culture broth. The present hypotriglyceridemically active polysaccharide can be used as an active ingredient of a hypotriglyceridemic or antiatherosclerotic pharmaceutical composition together with a pharmaceutically acceptable carrier therefor to form a hypotriglyceridemic or antiatherosclerotic pharmaceutical composition, which is suitable for oral administration to mammals. |
申请公布号 |
AU3048884(A) |
申请公布日期 |
1985.01.31 |
申请号 |
AU19840030488 |
申请日期 |
1984.07.11 |
申请人 |
ADVANCE KAIHATSU KENKYUJO K.K. |
发明人 |
YASUO KAWAI;KAZUNAGA YAZAWA |
分类号 |
C12P19/00;A61K31/715;A61K35/74;A61P1/16;A61P3/06;A61P3/08;A61P9/10;A61P9/12;C08B37/00;C12P1/04;C12P19/04;C12R1/46 |
主分类号 |
C12P19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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