| 发明名称 |
SUBSTITUTED ISOQUINOLINE DERIVATIVES |
| 摘要 |
Substituted isoquinolines of the formula <IMAGE> I wherein R is lower alkoxy, n is the integer zero or 1, and A is <IMAGE> <IMAGE> <IMAGE> wherein R1 is phenyl, halophenyl, lower-alkylphenyl or lower-alkoxyphenyl, and pharmaceutically acceptable acid addition salts thereof, are described. The compounds of formula I are useful in the treatment of cerebral and cardiac ischemias. |
| 申请公布号 |
ZA8403748(B) |
申请公布日期 |
1985.01.30 |
| 申请号 |
ZA19840003748 |
申请日期 |
1984.05.17 |
| 申请人 |
F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT |
发明人 |
HANS BRUDERER;SIDNEY TEITEL;JOHN G. MULLIN JR.;RICHARD WIGHTMAN KIERSTEAD;JAY PHILIP O'BRIEN;KEIJI NAKAMURA;MITSURU TATEISHI |
| 分类号 |
C07D295/20;A61K31/47;A61K31/472;A61K31/495;A61P7/02;A61P9/00;A61P9/10;A61P25/02;C07C233/45;C07D217/18;C07D217/20;C07D217/26;C07D241/04;C07D241/08;C07D295/205;C07D295/22;C07D295/24;C07D401/06 |
主分类号 |
C07D295/20 |
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