| 发明名称 |
1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
| 摘要 |
The invention provides compounds of the general formula (I) <CHEM> and physiologically acceptable salts, hydrates and bioprecursors thereof; e.g. 1-Methyl-N<5>-[3-[3-[(3-pyridinylmethyl)aminomethyl]phenoxy]propyl]-1H -1,2,4-triazole-3,5-diamine. The compounds of formula (I) show activity as histamine H2-antagonists. |
| 申请公布号 |
EP0029303(B1) |
申请公布日期 |
1985.01.30 |
| 申请号 |
EP19800303729 |
申请日期 |
1980.10.22 |
| 申请人 |
GLAXO GROUP LIMITED |
发明人 |
BRADSHAW, JOHN;CLITHEROW, JOHN, WATSON;BAYS, DAVID EDMUND;HAYES, ROGER;MACKINNON, JOHN WILSON MACFARLANE |
| 分类号 |
C07D249/14;A61K;A61K31/41;A61K31/42;A61K31/425;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61K31/47;A61K31/505;A61K31/53;A61P43/00;C07C271/22;C07D;C07D401/12;C07D403/12;C07D405/12;C07D405/14;C07D409/12 |
主分类号 |
C07D249/14 |
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