发明名称 N-substituted-amido-amino acids
摘要 Compounds of the formula <IMAGE> wherein R and R9 are independently hydroxy and lower alkoxy, R1 and R2 are independently hydrogen, lower alkyl, aryl-lower alkyl having from 7 to 12 carbon atoms, or heterocyclic-lower alkyl having from 6 to 12 carbon atoms, R3, R4, R5, R7 and R8 are hydrogen or lower alkyl, R6 is heterocyclic and their pharmaceutically acceptable, nontoxic acid addition salts and where R or R9 or both are hydroxy, their pharmaceutically acceptable, nontoxic basic salts, possess antihypertensive activity.
申请公布号 US4496542(A) 申请公布日期 1985.01.29
申请号 US19830484729 申请日期 1983.04.13
申请人 USV PHARMACEUTICAL CORPORATION 发明人 SKILES, JERRY W.;YOUSSEFYEH, RAYMOND D.;SUH, JOHN T.;JONES, HOWARD
分类号 A61K38/00;C07D233/56;C07D233/88;C07K5/02;(IPC1-7):A61K37/00;A61K31/40;A61K31/425;C07C103/52;C07D211/30;C07D211/56;C07D211/72;C07D215/00;C07D221/02;C07D233/00;C07D233/28;C07D233/66;C07D235/04;C07D265/30;C07D279/10;C07D403/00;C07D405/00;C07D413/00;C07D415/00 主分类号 A61K38/00
代理机构 代理人
主权项
地址