| 摘要 |
<p>Beta-lactamase inhibiting compounds of the formula <CHEM> or a pharmaceutically acceptable acid addition or carboxylate salt thereof; where n is zero, 1 or 2; X3 is H or Br, R<1> is H, the residue of certain carboxy-protecting groups or the residue of an ester group readily hydrolyzable in vivo; one of R<1><2> and R<1><3> is H and the other is vinyl, certain aryl, arythio, alkylthio, alkylsulfonyl or certain heterocyclyl, aminomethyl, thiocarboxamido or amidino groups; one of R<2> and R<3> is H and the other is as diclosed for the other of R<1><2> and R<1><3>, or is Cl or CH2OH, and R<1><8> is H or certain acyl groups; intermediates useful in their production, methods for their preparation and use, and pharmaceutical compositions containing them.</p> |
