发明名称 |
A protein having antitumor activity. |
摘要 |
<p>A protein having a polypeptide subunit containing an N-terminal amino acid sequence of Ser-Ala-Ser-Arg-Ala-Leu-Ser- Asp-Lys-Pro-Leu-Ala-His-Val- Val-Ala-Asn-Pro-Gln-Val-Glu-Gly-Gln-Leu-Gln-Trp-Leu. The protein is obtained in substantially pure form at high activity recovery, and is excellent in inducing necrosis of tumors with no toxicity upon the normal tissues of the living body. The protein is thermally stable and can be formulated into pharmaceutical compositions.</p> |
申请公布号 |
EP0132125(A2) |
申请公布日期 |
1985.01.23 |
申请号 |
EP19840304769 |
申请日期 |
1984.07.12 |
申请人 |
ASAHI KASEI KOGYO KABUSHIKI KAISHA;DAINIPPON PHARMACEUTICAL CO., LTD. |
发明人 |
HAYASHI, HIROSHI;KUWASHIMA, JUNJI |
分类号 |
A61K35/14;A61K35/16;A61K38/16;A61P35/00;C07K1/22;C07K14/435;C07K14/47;C07K14/525;C12P21/00;(IPC1-7):C07K1/00;A61K37/02 |
主分类号 |
A61K35/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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