发明名称 DEBROMINATION FOR DIBROMOPENICILLANIC ACID AND DERIVATIVES
摘要 A process for the debromination of 6-monobromo- and 6,6-dibromopenicillanic acid, and various derivatives thereof, by the action of a bisulfite salt. The debrominated compounds produced find various utilities, as beta-lactamase inhibitors useful in therapy in combination with known beta-lactam antibiotics, or as intermediates in the further synthesis of useful beta-lactam compounds.
申请公布号 JPS608293(A) 申请公布日期 1985.01.17
申请号 JP19840116338 申请日期 1984.06.06
申请人 PFIZER INC 发明人 DONARUDO KUREIN PIRII;POORU DAGURASU UIIKUSU
分类号 C07D499/87;A61K31/43;A61P31/04;C07D499/00;C07D499/86;C07D499/861;C07D499/897 主分类号 C07D499/87
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