| 摘要 |
Novel 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydropyridazines, particularly compounds of the formula I, <IMAGE> I wherein COOR1 and COOR2 are the same or different carboxylic acid ester groups, R3 is H or (C1-6)alkyl and R4 is H, (C1-6)alkyl, (C3-6)alkenyl or -alkynyl, (C3-7)cycloalkyl, (C4-8)cycloalkylalkyl, (C7-9)phenylalkyl or (C9-12) phenylalkenyl, the phenyl ring being unsubstituted or mono-, di- or trisubstituted independently by halogen, OH, (C1-4)alkyl or -alkoxy, for the treatment of coronary insufficiency, spasms in smooth muscles, hypertension or cerebrovascular insufficiency.
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