发明名称 N-ACETYL-P-AMINOPHENOL COMPOSITION CONTAINING PERTIALLY GELATINIZED STARCH AND METHOD FOR PREPARING SAME
摘要 An N-acetyl-p-aminophenol composition capable of being directly formed into a tablet having high hardness, short disintegration time and short dissolution time is disclosed. The composition includes N-acetyl-p-aminophenol, a pharmaceutically acceptable partially gelatinized starch, a pharmaceutically acceptable lubricant, water and optionally an auxiliary binder, an auxiliary disintegrant or both of these optional components. Also disclosed is a method for preparing the essential components (and optional components if desired) and spray drying the slurry.
申请公布号 ZA8403800(B) 申请公布日期 1984.12.24
申请号 ZA19840003800 申请日期 1984.05.18
申请人 MALLINCKRODT, INC. 发明人 ANIL MANOHAR SALPEKAR;STEVEN ROBERT FREEBERSYSER;DOUGLAS ARTHUR ROBINSON
分类号 A61K9/20;A61K31/165;A61K47/38;A61P25/04 主分类号 A61K9/20
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