摘要 |
1,4-dihydropyridine-3,5-dicarbonic acid esters having the formula (I), wherein R1 is hydrogen, a cyclo-alkyl comprising from 3 to 7 atoms of carbon or optionally a substituted alkyl comprising from 1 to 6 atoms of carbon; R2 and R5 represent independently from each other a hydrogen or an alkyl comprising from 1 to 6 atoms of carbon; R3 is an alkyl comprising from 1 to 12 atoms of carbon or independently -AR4 described hereunder, proportion included; R4 is a hydroxy, an alkoxy comprising from 1 to 12 atoms of carbon, -OCOR6, -NR7R8 or -NB; A is an alkylene comprising from 2 to 14 atoms of carbon; Q is an annulate fully unsaturated ring system, comprising at least 2 different ring hetero atoms, and having an aromatic character. Production thereof and pharmaceutical preparations containing them. |