发明名称 |
Binding assay for the detection of mycobacteria |
摘要 |
A method for detecting the presence of Mycobacteria in a fluid or tissue which comprises mixing the fluid or tissue containing a secretory product of Mycobacteria with a complex of a tracer-containing molecule and a binding macromolecule having reversible binding affinity for the tracer-containing molecule and detecting the tracer-containing molecule, wherein the tracer-containing molecule is a charcoal-adsorbable protein from Mycobacterium tuberculosis which has a molecular weight of 20,000-30,000 and which is immunochemically stable from 4 DEG C. to 250 DEG C. and has a pH range from 3.0 to 9.0. The method is particularly applicable to the detection of infectious tuberculosis in humans and determining the antibiotic sensitivity of infecting Mycobacteria.
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申请公布号 |
US4489158(A) |
申请公布日期 |
1984.12.18 |
申请号 |
US19820421956 |
申请日期 |
1982.09.23 |
申请人 |
MONTEFIORE HOSPITAL AND MEDICAL CENTER, INC. |
发明人 |
STRAUS, EUGENE W. |
分类号 |
C12P1/06;C12P21/00;C12Q1/04;C12Q1/18;G01N33/569;(IPC1-7):G01N33/54 |
主分类号 |
C12P1/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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