摘要 |
<p>Compounds of the structural formula: …<CHEM>… in which:… R is hydrogen or a lower alkyl of 1-6 carbons; and… R<1>, R<2> and R<3> are allyloxy, allylthio, halo or hydrogen, with the proviso that one of R<1>, R<2> and R<3> is allyloxy or allylthio; or a pharmaceutically acceptable acid addition salt thereof, a process for their preparation and their application as alpha 2-antagonists and as intermediates for preparing alpha 2-adrenergic affinity resins.</p> |