| 摘要 |
<p>Substituted benzophenones of the formula <IMAGE> (I) in which Ph represents unsubstituted or substituted phenyl and R represents free, esterified or amidated carboxy, have anti-inflammatory and/or analgesic properties and can be used as active ingredients in medicaments. They are manufactured, for example, as follows: a compound or a mixture of compounds of the formula <IMAGE> (II) in which X1 and X2 together represent a group of the formula -C(=O)-O that is bonded via the carbonyl group to the radical Ph and X3 represents hydrogen, or one of the radicals X1 and X3 represents a group of the formula -C(=O)-Z, the other represents hydrogen and X2 represents a group R'O- in which R' represents hydrogen or a hydroxy-protecting group, is subjected to acid treatment and the primary product is decomposed solvolytically.</p> |
