7A - SUBSTITUTED 3-OXO-17A-PREGN-4-EN-21.17-CARBOLACTONE METHOD FOR THE PREPARATION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

摘要

Novel 7 alpha -substituted 3-oxo-17 alpha -pregn-4-ene-21,17-carbolactones of the formula wherein is a CC single or CC double bond or the group R7 is the group SR', R' being a hydrogen atom or a straight-chain or branched alkyl residue of 1-6 carbon atoms optionally substituted by a hydroxy or acyloxy group, the group COOR'' or the group COR'' wherein R'' is an alkyl group of 1-4 carbon atoms and is a CC single bond or the group have antialdosterone activity with reduced endocrinological side effects.