发明名称 7-[Amino or carboxy substituted oxyimino]-3-[amino or alkoxy substituted heterocyclic thiomethyl] cephalosporin derivatives
摘要 Bacteriostatic cephem compounds and processes for preparing same having the formula: <IMAGE> wherein R1 is amino or protected amino, R2 is lower alkyl, amino(lower)alkyl, protected amino(lower)alkyl, hydroxy(lower)alkyl, protected hydroxy(lower)alkyl, lower alkylthio(lower)alkyl, carboxy(lower)alkyl, esterified carbony(lower)alkyl, (C3-C8)cycloalkyl, lower alkenyl or lower alkynyl, R3 is a heterocyclic group substituted with amino(lower)alkyl, protected amino(lower)alkyl, hydroxy(lower)alkyl or both amino and lower alkyl, R4 is carboxy or protected carboxy, provided that R3 is a heterocyclic group substituted with hydroxy(lower)alkyl or both amino and lower alkyl, when R2 is lower alkyl, and its pharmaceutically acceptable salt.
申请公布号 US4487767(A) 申请公布日期 1984.12.11
申请号 US19820379729 申请日期 1982.05.19
申请人 FUJISAWA PHARMACEUTICAL CO., LTD. 发明人 TAKAYA, TAKAO;MASUGI, TAKASHI;TAKASUGI, HISASHI;KOCHI, HIROMU
分类号 A61K;A61K31/545;C07D501/36;C07D501/56;(IPC1-7):A61K31/545 主分类号 A61K
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