Interferon gel formulations.

摘要

A kit for formulating and dispensing an alpha-type interferon gel composition comprising a) a vial having an open end aseptically sealed and containing about 1 x 10 to 5 x 10° International Units of lyophilized alpha-type interferon formulation prepared from an alpha-type interferon having a specific activity of at least 5 x 107 International Units/mg. total protein; and b) a tube having flexible walls and sealing means at its open end and containing a dermatologically acceptable vehicle which contains a compatible preservative and a sufficient amount of polyoxyethylene polyoxypropylene block polymer for the vehicle to be liquid at about 15°C. and below and which togethr with the lyophilized alpha-type interferon gels at 15°C. and above; and methods for preparing said gel using said kit.