发明名称 |
Method for the production of nuclear substituted cinnamoylanthranilic acid derivatives |
摘要 |
The present invention provides an improved method for producing a nuclear substituted cinnamoylanthranilic acid compound. Illustrative of the process is the reaction of 3,4-dimethoxybenzaldehyde with 2-carboxymalonanilic acid in an inert solvent medium in the presence of piperidine to provide an intermediate salt precipitate, and the salt is treated with an acidic reagent to yield N-(3,4-dimethoxycinnamoyl)anthranilic acid product.
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申请公布号 |
US4486597(A) |
申请公布日期 |
1984.12.04 |
申请号 |
US19840577758 |
申请日期 |
1984.02.07 |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD. |
发明人 |
IIZUKA, KINJI;KAMINO, TETSUHIDE;YAMAMOTO, RYOJI;HARADA, HIROMU |
分类号 |
C07C231/00;C07C231/12;C07C235/38;C07D295/02;C07D295/027;(IPC1-7):C07C99/00 |
主分类号 |
C07C231/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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