| 摘要 |
NEW MATERIAL:The furoindole compound of formula. USE:Analgesic and anti-inflamatory. PREPARATION:The compound of formula can be prepared e.g. by (1) hydrolyzing the 6-trifluoromethyl-4H-furo[3,2-b]indole-2-carboxylic acid ester with an alkali such as NaOH, KOH, etc. to obtain the corresponding carboxylic acid, (2) converting the acid to the corresponding acid chloride e.g. with thionyl chloride, (3) condensing the product with morpholine to obtain 2-morpholinocarbonyl- 6-trifluoromethyl-furo[3,2-b]indole, and (4) reacting the compound with 2-ethyl- hexanoyl chloride.
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