发明名称 Process for the preparation of o-(2,6-dichloroanilino)phenylacetic acid and its salts
摘要 By condensation of ortho-chlorophenylacetic acid with 2,6-dichloroaniline in the presence of a copper catalyst and of an alkali metal salt, ortho-(2,6-dichloroanilino)phenylacetic acid is obtained in one reaction step and in high yield. Preferably, the compound is converted into its sodium salt, which is the antirheumatic and analgesic known as diclofenac sodium.
申请公布号 CH646413(A5) 申请公布日期 1984.11.30
申请号 CH19810003008 申请日期 1981.05.08
申请人 OCG AG ORGANISATION FUER CHEMIE UND GALENIK 发明人
分类号 (IPC1-7):C07C101/44 主分类号 (IPC1-7):C07C101/44
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