SYNTHESIS OF 2-(METHYLSULFONYL)-5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOLE VIA OXIDATION OF 2-(METHYLTHIO)-5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOLE WITH A MOLYBDENUM OR TUNGSTEN CATALYST

摘要

The present invention provides processes of making thiadiazole sulfone. The present processes are used to make 2-(methylsulfonyl)-5--(trifluoromethyl)-1,3,4-thiadiazole. The 2-(methylsulfonyl)-5-(trifluoro--methyl)-1,3,4-thiadiazole is made using catalytic oxidation in the presence of a suitable oxidizing agent. The catalyst used for the oxidation reaction is a molybdenum or tungsten catalyst.