发明名称 SUBSTITUTED 1,5-NAPHTHYRIDINE AZOLIDINONES AS CDK INHIBITORS.
摘要 <p>The present invention provides novel, substituted 1,5-naphthyridine azolinones of formula (I) which inhibit Cdkl and are selective against Cdk2 and Cdk4. These compounds and their pharmaceutically acceptable salts have antiproliferative activity and are useful as anti-cancer agents.</p>
申请公布号 MX2007011982(A) 申请公布日期 2007.12.10
申请号 MX20070011982 申请日期 2006.03.24
申请人 F. HOFFMANN-LA ROCHE AG. 发明人 JIN-JUN LIU
分类号 C07D471/04;A61K31/435;A61P35/00 主分类号 C07D471/04
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