FOERFARANDE FOER FRAMSTAELLNING AV 6,7-BENSOMORFANDERIVAT VILKA AER ANVAENDBARA SOM ANALGETISKA MEDEL ANTAGONISTER FOER NAKOTISKA MEDEL OCH INHIBITORER FOER SEKRETION AV DET LUTEN ISRANDE HORMONET

摘要

6,7-Benzomorphan derivatives of formula I, (I) wherein R1 is hydrogen; optionally hydroxy- and/or alkoxy-substituted alkyl, alkenyl, alkynyl, cycloalkyl or cycloalkylalkyl; alkenyloxyalkyl, aralkyl, arylhydroxyalkyl, aralkenyl or tetrahydrofurylalkyl; or optionally alkyl-substituted furylalkyl or isoxazolylalkyl, R2 is hydrogen or methyl, R3 is hydrogen, alkyl, alkenyl, alkynyl, aralkyl, hydroxyalkyl of alkoxyalkyl and R4 is hydrogen, hydroxy, alkoxy or alkenyloxy, hydroxy groups in said compounds being each optionally acylated, having analgesic and luteinising hormone secretion inhibiting properties.