| 摘要 |
PURPOSE:To prepare novel antibiotic troposulfenin useful as a drug or an animal drug, having antifungal and antibacterial action, by cultivating a specific bacterium belonging to the genus Pseudomonas, separating and collecting troposulfenin from the culture. CONSTITUTION:A bacterium such as Pseudomonas troposulfenii sp.nov. (FERM-P 7042) belonging to the genus Pseudomonas, capable of producing novel antibiotic troposulfenin, is cultivated in a medium, and antibiotic froposulfenin shown by the formula I (R is H or CH3) is obtained by separating and collecting it from the prepared culture. Troposulfenin or troposulfenin S-methyl ether shown by the fomula II obtained by methylating it at a mercapto group of 8-position has antifungal and antibacterial actions, and is a novel antibiotic useful as a medicine and animal drug.
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