摘要 |
Substituted isoquinolines of the formula <IMAGE> I wherein R is lower alkoxy, n is the integer zero or 1, and A is <IMAGE> <IMAGE> <IMAGE> wherein R1 is phenyl, halophenyl, lower-alkylphenyl or lower-alkoxyphenyl, and pharmaceutically acceptable acid addition salts thereof, are described. The compounds of formula I are useful in the treatment of cerebral and cardiac ischemias. |
申请人 |
HOFFMANN-LA ROCHE & CO AG, F., |
发明人 |
HRUDERER, HANS,;KIERSTEAD, RICHARD WIGHTMAN,;MULLIN, JOHN G., JR.,;O`BRIEN, JAY PHILIP,;TEITEL, SIDNEY,;NAKAMURA, KEIJI,;TATEISHI, MITSURU, |