发明名称 |
SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES COATED WITH MANNAN, PREPARATION METHOD THEREOF AND CONTRAST AGENT FOR DIAGNOSING LIVER DISEASES |
摘要 |
A mannan-coated superparamagnetic iron oxide nanoparticle is provided, which enables specific flow of liver to kupffer cell and ensure stability of ferrofluid. A contrast media for diagnosing hepatism comprises a mannan coated superparamagnetic iron oxide nanoparticle. A method for manufacturing the nanoparticle comprises: a step of adding basic solution in iron chloride aqueous solution and dipping iron oxide nanoparticle; a step of oxidizing the iron oxide nanoparticle and producing storage solution; and a step of mixing mannan solution in the storage solution, stirring and coating.
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申请公布号 |
KR20090090104(A) |
申请公布日期 |
2009.08.25 |
申请号 |
KR20080015374 |
申请日期 |
2008.02.20 |
申请人 |
INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY |
发明人 |
YOO, MI KYUNG;PARK, IN KYU;JEONG, HWAN JEONG;JEONG, YONG YEON;KWON, JIN SOOK;CHO, CHONG SU |
分类号 |
A61K49/06;A61B5/055;A61K49/00 |
主分类号 |
A61K49/06 |
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