MELLANPRODUKTER FOR FRAMSTELLNING AV NYA 2-SUBSTITUERADE OCH 2,6-DISUBSTITUERADE PENEM-FORENINGAR

摘要

This invention relates to phosphorane compounds of the formula wherein Y is hydrogen, ethyl or hydroxyethyl, Q is phenyl or (lower) alkyl, R" is an easily removable ester group and X represents certain organic substituents. Also included in the invention are pharmaceutically acceptable salts of the above compounds and derivatives of the above compounds in which the carboxyl group at the 3- position is protected by an easily removable ester protecting group. The compounds of the present invention are of use as intermediates in the preparation of penem compounds having potent antibacterial activity.