发明名称 |
OXACEPHALOSPORINS, THEIR PREPARATION AND THERAPEUTIC AGENTS CONTAINING THEM |
摘要 |
New oxacephalosporins of the general formula <IMAGE> (I) in which R1 is a protective radical and (a) R4 is a substituted 2-(2-aminothiazol-4-yl)-acetyl radical of which the amine group is protected, or an alpha -carboxyarylacetyl radical, and R'' is hydrogen or methoxy in the 7 alpha -position, or alternatively (b) R4 is a protective radical and R'' is hydrogen or methoxy in the 7 alpha -position or hydrogen in the 7 beta -position, in the form of a bicyclooct-2-ene or bicyclooct-3-ene or a 3-oxoethylidenebicyclooctane, are useful as intermediates for the preparation of pharmaceutically active oxacephalosporins. |
申请公布号 |
DE3166633(D1) |
申请公布日期 |
1984.11.15 |
申请号 |
DE19813166633 |
申请日期 |
1981.11.19 |
申请人 |
RHONE-POULENC SANTE |
发明人 |
FARGE, DANIEL;LE ROY, PIERRE;MOUTONNIER, CLAUDE;PLAU, BERNARD;PEYRONEL, JEAN-FRANCOIS |
分类号 |
A61K31/535;A61P31/04;C07D501/24;C07D505/00;(IPC1-7):C07D498/04;A61K31/53 |
主分类号 |
A61K31/535 |
代理机构 |
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代理人 |
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地址 |
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