发明名称 beta -Lactam antibiotics
摘要 <p>This invention concerns intermediates for use in preparing beta -lactam antibiotics. More specifically the invention provides a compound of the formula <IMAGE> wherein R1 is hydrogen or acyl or the group R1-NH- is protected amino; R3 and R4 are the same or different and each is hydrogen, alkyl, cycloalkyl, phenyl or substituted phenyl, or one of R3 and R4 is hydrogen and the other is alkoxycarbonyl, alken-1-yl, alkyn-1-yl, 2-phenylethenyl or 2-phenylethynyl; V is a leaving group; and M<+> is hydrogen or a cation. It also provides similar compounds where R1 is a protecting group.</p>
申请公布号 GB2139618(A) 申请公布日期 1984.11.14
申请号 GB19830033191 申请日期 1983.12.13
申请人 E R * SQUIBB & SONS INC 发明人 RICHARD BROOK * SYKES;WILLIAM LAWRENCE * PARKER;CHRISTOPHER MICHAEL * CIMARUSTI;WILLIAM HENRY * KOSTER;WILLIAM ALLEN * SLUSARCHYK;ALAN WILLIAM * FRITZ;DAVID MACK * FLOYD
分类号 A61K31/395;A61K31/397;A61K31/41;A61K31/42;A61K31/425;A61K31/435;A61P31/04;C07C67/00;C07C301/00;C07C303/34;C07C307/02;C07D205/08;C07D205/085;C07D213/18;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D409/12;C07D409/14;C07D417/12;C07D471/04;C07F7/08;C07F7/10;C07F9/6558;C12P17/10;(IPC1-7):C07C143/86 主分类号 A61K31/395
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