摘要 |
NEW MATERIAL:A compound of formula I [R1 is cyano-substituted lower alkyl, lower alkylthio-lower-alkyl, lower cycloalkyl-lower alkyl, halogen-substituted lower-alkyl; 1,1-dioxotetrahydrothiophen-3-yl, tetrahydrothiopyran-4-yl, 1-(2-furyl) ethyl, 1-(3-thienyl)ethyl; R2 is lower alkyl; R3 is lower alkyl, lower alkoxy]. EXAMPLE:O-Methyl O-5-methoxy-2-nitrophenyl N-1-(cyanomethyl)ethyl thiono- phosphoric acid amide. USE:Plant disease-controlling agent. PREPARATION:The reaction of a thiophosphoric acid amide chloride of formula IIwith a phenol of formula III is carried out at an equivalent ratio 1-1.5 phenol to the chloride, usually in a solvent, where necessary, in the presence of 1-2 equivalent amount of an acid acceptor such as potassium carbonate and 0.01- 0.1 equivalent amount of a copper catalyst.
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