摘要 |
This specification discloses sensor electrodes, and their combination with reference electrodes; the manufacture of such electrodes; apparatus utilising such electrodes; and electrical circuitry into which such electrodes can be incorporated, specifically the establishment of certain design criteria in the production of such electrodes for lay, or clinic, use. …<??>The electrodes can be used in an invasive probe (i.e. one which enters body tissue to contact a body fluid such as whole blood or subcutaneous tissue fluid) or as part of an external test upon a withdrawn sample (using a syringe) or upon an expressed sample (e.g. using a needle-prick device). In the specification claims, sensor means for selective detection, measurement or monitoring of a given dissolved substrate in a mixture of dissolved substrates, comprising:-… (a) an area 4 of first electrode material comprising an enzyme catalytic of the said substrate and a mediator compound to transfer charge to the electrode when the enzyme is catalytically active, adjacent to but non-contiguous with;… (b) an area 5 of reference electrode material; both electrodes being of small dimension, and extending as or supported on an elongate member to facilitate manipulation before or during contact with live tissue or a small withdrawn sample of body fluid. |