| 摘要 |
Methods and compositions are provided for efficient production of polypeptides having insulin activity. The proinsulin gene is joined to secretion and processing signals for expression and secretion in yeast. The product may be obtained in enhanced yield in the nutrient medium. Cell line pYins1 was deposited at the A.T.C.C. on April 6, 1983 and given Accession No. 20670. |
