| 摘要 |
<p>In techniques for the analysis of genetic material, such as DNA and/or RNA, wherein the genetic material is denatured, fixed to a substrate and hybridized with a probe, superior results are obtainable when there is employed as the probe a chemically labeled probe which, preferably after hybridization, has added or attached thereto, such as to the chemical label or moiety of the probe, an enzyme component effective upon contact with a chromogen to produce an insoluble color precipitate or product. Techniques for the analysis of genetic material which are improved in sensitivity, definition, accuracy and/or speed, by employing a chemically labeled probe, include such well known techniques as <<Southern>> blot analysis, <<Northern>> blot analysis, <<Western>> blot analysis, colony hybridization, plaque lifts, cytoplasmic dot hybridization, in situ hybridization to cells and/or tissues and other such techniques.</p> |
