| 发明名称 |
Double ester of 16beta-ethylestran-17beta-ol derivatives. |
| 摘要 |
<p>A novel steroid compound of the formula
<Chemistry id="chema01" num="0001"><Image id="ia01" he="35" wi="78" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein A is a lower alkvlene group;
<Chemistry id="chema02" num="0002"><Image id="ia02" he="10" wi="8" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>is an acyl group; and <Image id="ia03" he="13" wi="6" file="IMGA0003.TIF" imgContent="character" imgFormat="TIFF" inline="yes" />is a single bond or a double bond, and methods of producing the compound (I) as follows:
<Chemistry id="chema03" num="0003"><Image id="ia04" he="35" wi="84" file="IMGA0004.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry><Chemistry id="chema04" num="0004"><Image id="ia05" he="39" wi="87" file="IMGA0005.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry><Chemistry id="chema05" num="0005"><Image id="ia06" he="34" wi="88" file="IMGA0006.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>and a pharmaceutical composition containing the compound (I). The compound (I) exhibits excellent antiandrogenic activity on oral administration and can be used for the treatment of prostatic hypertrophy.</p> |
| 申请公布号 |
EP0124252(A2) |
申请公布日期 |
1984.11.07 |
| 申请号 |
EP19840302076 |
申请日期 |
1984.03.27 |
| 申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
YOSHIMURA, YOSHINOBU;NISHIDA, YOKO;YASHIKI, TAKATSUKA |
| 分类号 |
A61K31/565;C07J1/00;C07J41/00;(IPC1-7):07J1/00;61K31/565;07J41/00 |
主分类号 |
A61K31/565 |
| 代理机构 |
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