发明名称 4-Haloalkylamino substituted chromanol useful as antihypertensive agent
摘要 A compound of the formula (I): <IMAGE> (I) and pharmaceutically acceptable salts thereof wherein R1 is hydrogen or C1-6 alkyl or an acyl group of 1 to 8 carbon atoms; n is 2, 3 or 4; X is halogen; and the OR1 and HN(CH2)nX moieties are trans; has anti-hypertensive activity and a low level of cardiac side-effects.
申请公布号 US4481213(A) 申请公布日期 1984.11.06
申请号 US19820398553 申请日期 1982.07.15
申请人 BEECHAM GROUP LIMITED 发明人 EVANS, JOHN M.
分类号 A61K31/35;A61K31/352;A61P9/12;C07D311/68;(IPC1-7):A61K31/35;C07D311/02 主分类号 A61K31/35
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