发明名称 Micro-channel chip
摘要 A micro-channel chip comprises two gas control channels, a liquid inlet channel, a liquid outlet channel, a piston channel, and a micro pump including two micro-valves and a plurality of micro-channels. One of the gas control channels communicates with one end of the piston channel and communicates with the two micro-valves and the liquid inlet channel respectively via the micro-channels. The other one of the gas control channels communicates with the two micro-valves and the liquid outlet channel respectively via the micro-channels. The other end of the piston channel communicates with one of the micro-valves via the micro-channels.
申请公布号 US9446403(B2) 申请公布日期 2016.09.20
申请号 US201214353337 申请日期 2012.10.23
申请人 XIAMEN XINCHUANG BIOLOGICAL TECHNOLOGY CO., LTD. 发明人 Peng Xingyue
分类号 G01N33/00;B01L3/00;G01N35/10 主分类号 G01N33/00
代理机构 代理人
主权项 1. A micro-channel chip, integrated as a single layer or multi-layer, comprising two gas control channels (GC1, GC2), disposed perpendicular to each other, to control a gas flow each contained therein; a liquid inlet channel, disposed perpendicularly without intersecting to GC1, a liquid outlet channel, disposed perpendicularly without intersecting to GC2, JC1 and JC2, two square micro-channels, disposed respectively in quadrant III and quadrant I in a Cartesian plane, in communication to Valve 1 and Valve 2 disposed respectively in quadrant II and quadrant IV in the Cartesian plane; a piston channel, integrated with Valve 1 for the piston channel and Valve 1 to operate under a same signal of gas pressure, the piston channel being much longer than each of valve channels of Valve 1 and Valve 2, such that Valve 1 and Valve 2 can be closed at high pressures much earlier than a liquid in the piston channel is driven to the liquid outlet channel, and a micro pump, controlled by an ordered loop of digital commands of a 1-by-2 matrix, beginning with (1, 1), followed by (0,1), then by (1,0) and back to (1,1), corresponding respectively to a gas pressure of GC1 and GC2, the micro pump, made of any materials, which includes the two micro-valves Valve 1 and Valve 2, which open at a command denoting a low gas pressure, and close at a command denoting a high gas pressure, by deforming under a pressure difference resulting from a surface tension, and Valve 1 and the piston channel being integrated to operate under identical signals of pressure, and a plurality of micro-channels, joining each other at a plurality of joints (M's), which are holes of a size substantially smaller than that of the micro-channels as passages for the liquid unless otherwise closing off under the a high pressure difference; one of said gas control channels (GC1) communicating with one end of said piston channel and communicating with said two micro-valves and said liquid inlet channel respectively via said micro-channels, the other one of said gas control channels (GC2) communicating with said two micro-valves and said liquid outlet channel respectively via said micro-channels, the other end of said piston channel communicating with one of said micro-valves via said micro-channels, wherein I) when a liquid inputs to the input channel: both GC1 and GC2 are initialized with a high pressure to make Valve 1 and Valve 2 close; II) GC1 switched to a low pressure to release Valve 1 to open for the liquid to flow into the piston channel; III) when the piston channel is filled with the liquid: GC1 switched to a high pressure to close Valve 1, and GC2 switched to a low pressure to release Valve 2 to open, making the liquid to flow from the piston channel to the outlet channel, not to the inlet channel; and IV) when the outlet channel is filled with the liquid from the piston channel: GC2 switched to a high pressure to close Valve 2.
地址 Xiamen, Fujian CN