System and method for neuromodulation

摘要

A method of treating autonomic imbalance in a patient includes energizing a first therapeutic element disposed to deliver therapy to a parasympathetic nerve fiber (e.g. vagus nerve), and energizing a second therapeutic element to deliver therapy to a sympathetic cardiac nerve fiber. At least one of the therapeutic elements is disposed in the vasculature superior to the heart. The therapy decreases the patient's heart rate and elevates or maintains the blood pressure of the patient.

主权项

1. A method of treating autonomic imbalance in a patient having a heart rate and a blood pressure, comprising:
delivering neuromodulation therapy to sustain or increase the blood pressure while decreasing the heart rate, said neuromodulating therapy including
(a) stimulating at least one extravascular parasympathetic nerve fiber using at least one first intravascularly-positioned electrode; and(b) stimulating at least one extravascular cardiac sympathetic nerve fiber using at least one second intravascularly-positioned electrode, wherein said method includes placing the second electrode in a posterior portion of a blood vessel.