发明名称 |
A method for stabilizing tissue plasminogen activator and a stable aqueous solution or powder containing the same. |
摘要 |
<p>A method for stabilizing a tissue plasminogen activator which involves adding to an aqueous solution or powder containing a tissue plasminogen activator an effective amount of a purified gelatin is disclosed. A stable aqueous solution or powder which contains a tissue plasminogen activator and an effective amount of a purified gelatin is also disclosed. The method and composition eliminate the problem of adsorption of tissue plasminogen activator to various laboratory equipment, and also prevent the conversion of the single-chain tissue plasminogen activator into a double-chain tissue plasminogen activator.</p> |
申请公布号 |
EP0123304(A2) |
申请公布日期 |
1984.10.31 |
申请号 |
EP19840104514 |
申请日期 |
1984.04.19 |
申请人 |
ASAHI KASEI KOGYO KABUSHIKI KAISHA;KOWA COMPANY, LTD. |
发明人 |
MURAKAMI, AKIRA;YOSHIZAKI, HIDEO |
分类号 |
A61K9/08;A61K38/00;A61K47/42;C12N9/72;C12N9/96;(IPC1-7):12N9/96;61K37/54 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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